Ginnifer Goodwin and Lana Parrilla had previously worked together as regular characters in Seasons 1-6 of Once Upon a Time (2011), playing Snow White and the Evil Queen respectively.
Lana Parrilla wore corsets and shaping garments appropriate to the 1949 setting throughout the six-month production. She said the restrictive clothing made it difficult to sit, walk and even talk while filming.
Both seasons are anthologies, but 7 actors crossed over as different characters: Jack Davenport, Lindsey Kraft, Kevin McNamara, Victoria Kelleher, Shaw Jones, Holland Clement and Mark Jude Sullivan.
Jack Davenport and Lana Parrilla worked together on Swingtown. The series was a period and relationship drama about the impact of sexual and social liberation in the 1970s. (Wikipedia).
Allison Tolman appeared in Season 2 and had previously played the lead character Nan in the short-lived ABC series Downward Dog (2017). Kirby Howell-Baptiste plays Taylor in Season 1's 2019 storyline and played Nan's best friend Jenn in Downward Dog (2017).
To prepare for her character in the late 1940s setting, Allison Tolman studied films from that era and drew particular inspiration from Katharine Hepburn and the film Adam's Rib (1949).
Ginnifer Goodwin plays Beth Ann, who befriends her husband's mistress. Ginnifer Goodwin appeared in Big Love (2007), which had a storyline in which a wife befriends a woman her husband has begun dating.